The Bioteck Academy platform is continually updated with papers by the leading experts in regenerative medicine


A one-stop shop for free referencing, an annotated collection of scientific literature in the field of regenerative medicine and surgery. Papers, collections of case histories, collaborations, scientific or clinical protocols can be immediately downloaded in PDF format. Where copyright laws do not allow it, you will find the abstract and the direct link to the publishers’ website.

In the past 20 years, we have witnessed the proliferation of scientific literature which, sometimes in an unruly manner, has added rather unclear information and indications that have not always been backed by solid data.

Bioteck Academy is centered around its Web platform which, with its training offers and recommended reading, contributes to providing orientation of this most fascinating of fields.

The Bioteck Academy platform is continually updated with the papers by the leading experts in regenerative medicine, specializing in dentistry, maxillofacial surgery, orthopedics and neurosurgery, and thanks to the members of the clinical community.

The Annotated Bibliography

The bibliography is curated by Bioteck Academy. It contains a complete bibliographical index of our collection of literature.

Always at your fingertips, use it as a guiding beacon in the field of regenerative medicine.

The publication is updated several times a year. The publications are sorted by subject and field of application.


Download the annotated bibliography to always have an index of our collection of literature at your fingertips.

The Bioteck Academy sheets

The Bioteck Academy sheets are an invaluable tool of scientific communication placed at the disposal of the community of experts in regenerative medicine. Their structured format allows the reader to easily browse the contents and to find inspiration for further reading and in-depth research. The sheets are color coded according to their subject: clinical practice, technology or basic research. The clinical sheets bring together an impressive range of cases treated by prominent Italian and foreign surgeons.

Find and download the Bioteck Academy sheets using our search engine, by selecting “Sheets” in the Document Type field.


Allografts versus Equine Xenografts in Calcaneal Fracture RepairDisplaced intra-articular calcaneal fractures are difficult to treat. We determined the functional results and complications of using allografts or equine xenografts in treating these fractures.

Authors: Armagan R. , Eren T. , Sonmez M. M. , Ugurlar M.
orthopedicsarticle2017armagan-r eren-t sonmez-m-m ugurlar-m
Coronally Advanced Flap Technique to Treat Class I and II Gingival Recession in Combination with Connective Tissue Graft or Equine Collagen Matrix: A Retrospective Study.This retrospective study aimed to compare the effectiveness of an equine collagen matrix (ECM) with that of a subepithelial connective tissue graft (CTG) in patients affected by Class I and II gingival recessions treated with a coronally advanced flap (CAF) technique2017Dentistry
The Zymo-TeckA cutting-edge biotechnological process to obtain tissue substitutes having unique properties.

Author: Bioteck Scientific Department
A comparative clinical study between bone onlay graft and connective tissue graft in reconstruction of Interdental papillae between two implantsGingival esthetics has become a decisive factor in the overall success of an implant-supported restoration, Successful implant therapy is no longer judged by whether or not the implant simply osseointegrates. The aim of the present study was to clinically evaluate and compare between bone graft and connective tissue graft in reconstruction of inter-implants papillae.

Authors: Abuo-Elfadl K. , Dardir A. M. , El Rahman R. A. , Shoeib M. , Ul-Dahab O. A.
dentistryarticle2011abuo-elfadl-k dardir-a-m el-rahman-r-a shoeib-m ul-dahab-o-a
The use of flexible xenogenic bone substitutes for maxillary sinus floor augmentationThis study was conducted for evaluation of the efficacy of osteoplant flex sheets (Xenogenic bone substitute) in sinus lifting procedures.

Authors: Elmonem K.A. , Katamish M.A.
dentistryarticle2014elmonem-k-a katamish-m-a
Comparison of autologous and heterologous bone graft stability effects for filling maxillary bone gap after Le Fort I osteotomyBACKGROUND: The amount of postoperative maxillary relapse of two different bone graft materials after Le Fort I osteotomy were compared in this study. OBJECTIVES: The aim of this study is to compare postoperative maxillary relapse rates using heterologous and autologous graft materials after Le Fort I osteotomy.

Authors: Eser C. , Gencel E. , Gokdogan M. , Kesiktas E. , Yavuz M.
dentistryarticle2015eser-c gencel-e gokdogan-m kesiktas-e yavuz-m
Regenerating a vertical bone defect consequent to peri-implantitisa GBR case with an equine enzyme-treated bone substitute and a resorbable equine collagen

Author: Tarquini G.
Effectiveness of hydrogen peroxide and electron-beam irradiation treatment for removal and inactivation of viruses in equine-derived xenograftsBone grafting is a common procedure for bone reconstruction in dentistry, orthopedics, and neurosurgery. A wide range of grafts are currently used, and xenografts are regarded as an interesting alternative to autogenous bone because all mammals share the same bone mineral component composition and morphology

Authors: Cusinato R. , Fattori P. , Martello T. , Morroni M. , Pacenti M. , Palù G.
2016Experimental data
experimental-dataarticle2016cusinato-r fattori-p martello-t morroni-m pacenti-m palu-g
Open-wedge high tibial osteotomycomparison between manual and computer-assisted techniques

Authors: Conteduca F. , Di Sette P. , Ferretti A. , Giannetti S. , Iorio R. , Pagnottelli M. , Papandrea P. , Vadalà A.
orthopedicsarticle2013conteduca-f di-sette-p ferretti-a giannetti-s iorio-r pagnottelli-m papandrea-p vadala-a
Cartilage regeneration revisited: entering of new one-step procedures for chondral cartilage repairThis article reviews the evolution of cartilage regeneration therapeutic approaches from two-step cell-based autologous chondrocyte implantation procedures to current one-step cell-free scaffold-assisted cartilage repair approaches for chondral cartilage repair. In particular, our research is focused on clinical data about commercially available cell-free implants used in regenerative medicine approaches for the treatment of chondral cartilage defects.

Authors: Freymann U. , Kaps C. , Petersen W.
orthopedicsarticle2013freymann-u kaps-c petersen-w
Effect of low-level laser on guided tissue regeneration performed with equine bone and membrane in the treatment of intrabony defects: a clinical study.The purpose of the present study was to evaluate the clinical results of guided tissue regeneration (GTR) after the application of equine bone and membrane alone or combined with low-level laser therapy (LLLT) for the treatment of periodontal defects

Authors: Demir T. , Dogan G. E. , Orbak R.
dentistryarticle2014demir-t dogan-g-e orbak-r
Arthroscopic knee cartilage repair with covered microfracture and bone marrow concentrateIn recent years several single-stage cartilage repair approaches have been devised to treat focal cartilage lesions. These usually associate microfracture (MFX) and a coverage scaffold. We describe a novel arthroscopic technique that combines MFX, autologous bone marrow concentrate (BMC), and a protective scaffold

Authors: Busilacchi A. , Calcagno S. , Cecconi S. , Enea D.
orthopedicsarticle2012busilacchi-a calcagno-s cecconi-s enea-d
Guided bone regeneration of an atrophic mandible with a heterologous bone blockThe aim of this work was to test the effectiveness of using enzymatically deantigenated equine bone block as a scaffold for guided bone regeneration (GBR) during a horizontal augmentation of the lower jaw

Author: Riboli F.
GBR-based restoration of a peri-implant defect with an equine flexible cortical bone membrane and heterologous equine bone.Objectives: To assess the efficacy of peri-implant defect restoration based on the use of partially decalcified equine cortical bone membrane and heterologous equine bone

Authors: Cremaschini S. , Gherlone E. , Pagnutti S. , Vinci G.
dentistryarticle2011cremaschini-s gherlone-e pagnutti-s vinci-g
Subantral filling by deantigenated heterologous bone and immediate fixture placementAIM: A successful implant therapy depends on sufficient quantity of available bone. Latero-posterior maxillary area often represents a hardly useful zone for routine implant therapy in long time edentulous patients. Standard procedures of maxillary sinus lifting are the goals of implant-prosthetic rehabilitation. Among different grafting materials used in this kind of procedures, the deantigenated heterologous bone reliability has been tested.

Authors: Cipriano L. , De Biase A. , Guerra F. , Lamazza L. , Tucci E.
dentistryarticle2005cipriano-l de-biase-a guerra-f lamazza-l tucci-e
Histomorphometric comparison of enzyme-deantigenic equine bone and anorganic bovine bone in sinusPURPOSE: To conduct a histomorphometric investigation comparing the use of enzyme-deantigenic equine bone (EDEB) and anorganic bovine bone (ABB) for maxillary sinus augmentation

Authors: Cinci L. , Gastaldi G. , Gherlone E. , Pieri L. , Vinci R.
dentistryarticle2015cinci-l gastaldi-g gherlone-e pieri-l vinci-r
3D radiology in dentistryA traditional radiography is a two-dimensional image of something that actually has three dimensions. At last, thanks to 3D radiological system with a small field of view we have the missing dimension, which exponentially amplifies our knowledge.

Authors: Ambu E. , Ghiretti R. , Laziosi R.
2013Dentistrydentistrybook2013ambu-e ghiretti-r laziosi-r
Managing a vestibular infra-bony periodontal defect in the aesthetic zone through bone regeneration: a case reportVestibular-only, infra-bony defects in the aesthetic zone represent a challenging condition for bone regeneration. The aim of the present report is to present a case where, grafting enzymatic-deantigenic, collagen preserved, bone substitutes, it was possible to reduce infra-bony pocket depth, recovering gingival heath and obtaining a good aesthetic outcome2013Dentistry
Case of severe bone atrophy of the posterior maxilla rehabilitated with blocks of equine origin bone: histological resultsPURPOSE: To report the histological outcomes of a case of bilateral severely resorbed posterior maxilla augmented with the use of blocks of enzymatically deantigenated equine bone.

Authors: Felice P. , Lizio G. , Pisacane A. , Pistilli R. , Signorini L.
dentistryarticle2013felice-p lizio-g pisacane-a pistilli-r signorini-l
Type I collagen in xenogenic bone material regulates attachment and spreading of osteoblasts over the beta1 integrin subunitXenogenic bone biomaterials have been proposed as an alternative to autografts or allografts in human bone restoring or in complement of prosthetic surgery

Authors: Basle M. F. , Chappard D. , Grizon F. , Lesourd M. , Pascaretti C.
1998Collagen Bone Properties
collagen-bone-propertiesarticle1998basle-m-f chappard-d grizon-f lesourd-m pascaretti-c
The use of cortical heterologous sheets for sinus lift bone grafting: a modification of Tulasne’s technique with 7-year follow-upIn this article, the authors describe their experience with using cortical deantigenated equine bone sheets in sinus lift grafting procedures performed on 23 patients.

Authors: Ammirabile G. , Cazzaniga A. , Celletti R. , Ludovichetti M.
dentistryarticle2013ammirabile-g cazzaniga-a celletti-r ludovichetti-m
Evaluation of the effect of heterologous type I collagen on healing of bone defectsPURPOSE: The purpose of this investigation was to evaluate the effect of type I collagen on the healing of bone defects both experimentally and clinically.

Authors: Gungormus M. , Kaya O.
2002Collagen Bone Properties
collagen-bone-propertiesarticle2002gungormus-m kaya-o
Type I collagen induces expression of bone morphogenetic protein receptor type IIThe extracellular matrix regulates many fundamental cellular processes such as proliferation, migration, and differentiation. Among the ECM components, type I collagen induces endothelial tube formation in vitro

Authors: Regazzoni C. , Rohrer L. , Winterhalter K. H.
2001Collagen Bone Properties
collagen-bone-propertiesarticle2001regazzoni-c rohrer-l winterhalter-k-h
Lateral ridge augmentation using an equine flex bone block infused with recombinant human plateletderived growth factor BB: a clinical and histologic studyThis paper reports on a patient who underwent horizontal ridge augmentation using recombinant human platelet-derived growth factor BB (rhPDGF-BB) in combination with a collagenate equine block

Authors: De Angelis N. , Scivetti M.
dentistryarticle2011de-angelis-n scivetti-m
Evaluation of two treatment modalities for patients with combination syndrome suffering from narrow anterior maxillaBackground: The success of a single maxillary denture in Combination syndrome relies on the principles of retention, stability and support. Severely resorbedmaxillary edentulous ridges that are narrow and constricted with increased inter ridge space will affect this success.

Authors: Riham O. I. , Tamer O. I.
dentistryarticle2013riham-o-i tamer-o-i
Human osteoclast formation and activity on an equine spongy bone substituteThe aim of the present study was to evaluate the in vitro formation and activity of human osteoclasts (OCLs) generated on a new type of xenograft for bone substitution, an equine spongy bone.

Authors: Nicholls B. M. , Perrotti V. , Piattelli A.
2009Experimental data
experimental-dataarticle2009nicholls-b-m perrotti-v piattelli-a
Interaction of osteogenin, a heparin binding bone morphogenetic protein, with type IV collagenOsteogenin, an extracellular matrix component of bone, is a heparin binding differentiation factor that initiates endochondral bone formation in rats when implanted subcutaneously with an insoluble collagenous matrix. We have examined the interaction of osteogenin with various extracellular matrix components including basement membranes.

Authors: Kleinman H. K. , Nandedkar A. K. , Paralkar V. M. , Pointer R. H. , Reddi A. H
1990Collagen Bone Properties
collagen-bone-propertiesarticle1990kleinman-h-k nandedkar-a-k paralkar-v-m pointer-r-h reddi-a-h
Dissociative extraction and reconstitution of extracellular matrix components involved in local bone differentiationSubcutaneous implantation of demineralized diaphyseal bone matrix in allogeneic rats results in the local induction of endochondral bone differentiation. We have explored the potential of three dissociative extractants, 4 M guanidine hydrochloride (Gdn . HCl), 8 M urea/1 M NaCl, and 1% NaDodSO4 at pH 7.4, containing protease inhibitors to solubilize putative inductive molecules in the bone matrix

Authors: Reddi A. H , Sampath T. K.
1981Collagen Bone Properties
collagen-bone-propertiesarticle1981reddi-a-h sampath-t-k
Horizontal-guided bone regeneration using a titanium mesh and an equine bone graftThe present work describes a horizontal ridge augmentation in which a titanium mesh was preshaped by adapting it to a stereolithographic model of the patient's jaw that was fabricated from CT scans. BACKGROUND: Guided bone regeneration (GBR) involves covering the augmentation site with a long-lasting barrier to protect it from the invasion of surrounding soft tissues. Among barriers, titanium meshes may provide a successful outcome, but the intraoperatory time needed to shape them is a disadvantage

Authors: Cinci L. , Pieri L.
dentistryarticle2015cinci-l pieri-l
Comparison of postoperation bone defects healing of alveolar processes of maxilla and mandible with the use of Bio-Gen and Bio-OssBone defects of mandible and maxilla alveolar processes have often iatrogenic origins, because they appear as a consequence of performed operations. Bone atrophy may be stopped by filling bone defects with augmentative biomaterial directly after an oral surgery procedure

Authors: Koszowski R. , Pająk J. , Śmieszek-Wilczewska J.
dentistryarticle2010koszowski-r pajak-j smieszek-wilczewska-j
Alveolar ridge regeneration with equine spongy bonea clinical, histological, and immunohistochemical case series

Authors: Artese L. , Iezzi G. , Pagnutti S. , Perrotti V. , Piattelli A. , Piccirilli M.
dentistryarticle2009artese-l iezzi-g pagnutti-s perrotti-v piattelli-a piccirilli-m
Vertical ridge augmentation using a flexible heterologous cortical bone sheet: three-year follow-upRehabilitation of the atrophic alveolar ridge is often problematic. Bone augmentation surgery may be hindered by a lack of surfaces from which blood vessels can spread during the initial stages of bone regeneration

Authors: Celletti R. , Ludovichetti F. S. , Ludovichetti M. , Pagnutti S. , Vaccari E.
dentistryarticle2011celletti-r ludovichetti-f-s ludovichetti-m pagnutti-s vaccari-e
The effect on osteogenesis of type I collagen applied to experimental bone defectsThe purpose of the present investigation was to evaluate the effects of type I collagen sponge on the healing of bone defects.

Author: Gungormus M.
2004Collagen Bone Properties
Cell-matrix interaction in boneType I collagen modulates signal transduction in osteoblast-like cells

Authors: Clemens T. L. , Green J. , Kleeman C. R. , Schotland S. , Stauber D. J.
1995Collagen Bone Properties
collagen-bone-propertiesarticle1995clemens-t-l green-j kleeman-c-r schotland-s stauber-d-j
Cell-matrix interaction in bone: type I collagen modulates signal transduction in osteoblast-like cellsCell interaction with extracellular matrix (ECM) modulates cell growth and differentiation

Authors: Clemens T. L. , Green J. , Kleeman C. R. , Schotland S. , Stauber D. J.
1995Collagen Bone Properties
collagen-bone-propertiesarticle1995clemens-t-l green-j kleeman-c-r schotland-s stauber-d-j
Complete reconstruction of edentulous mandible and maxilla using the Q-Implant System and applying the two-phase implantation with early loadingThe case described presents an unconventional concept for the reconstruction of a patient’s masticatory organ featuring early loading with the Q-Implant implantation system (Trinon Titanium GmbH)

Authors: Krezlik A. , Krezlik E.
dentistryarticle2004krezlik-a krezlik-e
Managing an extreme peri-implantitisPeri-implantitis leads to gradual peri-implant bone loss. Severe and extreme cases lead to complete implant failure and imply lost implants have to be removed. The aim of the present report is to present a case where an extreme peri-implantitis, causing complete peri-implant bone loss, was managed successfully2013Dentistry
Maxillary sinus lift through heterologous bone grafts and simultaneous acid-etched implants placement. Five year follow-upThe aim of this study was to assess retrospectively at 5 years the clinical outcome of bone regeneration in patients who underwent maxillary sinus lift with different equine derived, enzyme-deantigenated equine bone grafts, and simultaneous placement of acid etched surface implants.

Authors: Boato C. , Gazzola F. , Ludovichetti M. , Pagnutti S. , Stellini E. , Stievano D.
dentistryarticle2008boato-c gazzola-f ludovichetti-m pagnutti-s stellini-e stievano-d
Bone formation following sinus augmentation with an equine-derived bone grafta retrospective histological and histomorphometric study with 36-month follow-up

Authors: Cinci L. , Gastaldi G. , Gherlone E. , Pieri L. , Polizzi E. M. , Vinci R.
dentistryarticle2016cinci-l gastaldi-g gherlone-e pieri-l polizzi-e-m vinci-r
Application of the enzymatic deantigenation system in the reduction of the bacterial elements in human bone tissue

Authors: Carlone N. A. , Maggi S. , Mandras N. , Roana J. , Tullio V.
2006Enzymatic process
enzymatic-processarticle2006carlone-n-a maggi-s mandras-n roana-j tullio-v
The use of heterologous bone replacement together with platelet growth factor during vertebral surgery: critical analysis and preliminary resultsThe authors present case histories relating to experience gained over 18 months of using deantigenic osseous grafts together with platelet growth factor for posterior spine arthrodesis

Authors: Ascani C. , Ascani E. , Tornatore I.
orthopedicsarticle2005ascani-c ascani-e tornatore-i
Treatment of a bone defect consequent to the removal of a periapical cyst with equine bone and equine membranes: clinical and histological outcomeThe objective of this study was the clinical and histological assessment of such materials: equine bone granules, an equine collagen membrane and an equine pericardium membrane

Authors: Ammirabile G. , Cinci L. , Pieri L.
dentistryarticle2012ammirabile-g cinci-l pieri-l
Alveolar ridge regeneration with equine spongy bone: a clinical, histological, and immunohistochemical case seriesBACKGROUND: In the case of localized ridge atrophy, a ridge augmentation procedure, with the use of bone substitutes and barrier membranes, may then be necessary. PURPOSE: The aim of the present study was a clinical, histological, and immunohistochemical evaluation of an equine spongy bone in alveolar ridge augmentation procedures.

Authors: Artese L. , Iezzi G. , Pagnutti S. , Perrotti V. , Piattelli A. , Piccirilli M.
dentistryarticle2009artese-l iezzi-g pagnutti-s perrotti-v piattelli-a piccirilli-m
Effect of bone graft biomaterials at different chemical composition and geometry on human Bone Marrow Stromal Cells osteogenic differentiationIntroduction: For the repair of bone defects, a tissue engineering approach would be to combine cells capable of osteogenic (i.e. bone forming) activity with an appropriate scaffolding material to stimulate bone regeneration and repair.

Authors: Cancedda R. , Conserva E. , Foschi F. , Mastrogiacomo M. , Pera P.
2009Experimental data
experimental-datapresentation2009cancedda-r conserva-e foschi-f mastrogiacomo-m pera-p
Maxillary sinus lift with a collagenic equine heterologous bone substitute. Histomorphometric analysisObjectives: In this article, the authors describe their use of a heterologous equine collagen bone substitute for a maxillary sinus lift, and they assess the efficacy of this biomaterial when utilized with autologous bone

Authors: Ludovichetti M. , Pagnutti S.
dentistryarticle2011ludovichetti-m pagnutti-s
The size exclusion characteristics of type I collagenImplications for the role of noncollagenous bone constituents in mineralization

Authors: Lim J. E. , Price P. A. , Toroian D.
2007Collagen Bone Properties
collagen-bone-propertiesarticle2007lim-j-e price-p-a toroian-d
Use of collagen scaffold and autologous bone marrow concentrate as a one-step cartilage repair in the kneeHistological results of second-look biopsies at 1 year follow-up

Authors: Calcagno S. , Cecconi S. , Enea D. , Manzotti S. , Ramazzotti D.
orthopedicsarticle2011calcagno-s cecconi-s enea-d manzotti-s ramazzotti-d
Treatment of mandibular atrophy by an equine bone substitute: an immunohistochemical study in manObjective : To perform an immunohistochemical evaluation of microvessel density (MVD), vascular endothelial growth factor (VEGF) and nitric oxide synthase (NOS) expression in mandibular ridge regeneration using an equine derived bone substitute.

Authors: Artese L. , Di Gregorio G. , Iezzi G. , Pagnutti S. , Perrotti V. , Piccirilli M.
dentistryarticle2012artese-l di-gregorio-g iezzi-g pagnutti-s perrotti-v piccirilli-m
Effect of type I collagen on the adhesion, proliferation, and osteoblastic gene expression of bone marrow derived mesenchymal stem cellsOBJECTIVE: To investigate the effects of porous poly lactide-co-glycolide (PLGA) modified by type I collagen on the adhesion, proliferation, and differentiation of rabbit marrow-derived mesenchymal stem cells (MSCs)

Authors: Hu Y. Y. , Liu G. , Lu R. , Wu S. J. , Xiong Z. , Zhao J. N.
2004Collagen Bone Properties
collagen-bone-propertiesarticle2004hu-y-y liu-g lu-r wu-s-j xiong-z zhao-j-n
Treatment of a ridge atrophy and two peri-implant defects with equine bone and an equine pericardium membrane: clinical and histological outcome2013Dentistry
Type I collagen-induced osteoblastic differentiation of bone-marrow cells mediated by collagen-alpha2beta1 integrin interactionBone marrow cells are multipotent cells. When bone marrow cells were cultured with type I collagen matrix gels, they showed high alkaline phosphatase activity, collagen synthesis, and formed mineralized tissues. Furthermore, cells expressed osteocalcin and bone sialoprotein genes, which are osteoblast-specific genes. These findings indicate that type I collagen matrix gels induce osteoblastic differentiation of bone marrow cells

Authors: Fujisawa R. , Kuboki Y. , Mizuno M.
2000Collagen Bone Properties
collagen-bone-propertiesarticle2000fujisawa-r kuboki-y mizuno-m
Osteo-promoting activity of OSTEOPLANT ANGIOSTAD in vitroThere is an increasing need for an appropriate and readily-available material to reconstruct large bone defects, one of the most significant problems in the dental and maxillo-facial fields. The in vitro study examines the effects of OSTEOPLANT ANGIOSTAD, a product developed to increase osteoinductivity.

Authors: Bellone G. , Emanuelli G. , Scirelli T.
2008Experimental data
experimental-dataarticle2008bellone-g emanuelli-g scirelli-t
Equine-derived bone substitutes in orthopedics and traumatology: authors’ experienceAIM: To evaluate the use of equine-derived bone grafts in the treatment of bone loss in a heterogeneous clinical case series.

Authors: Barbera P. , Bonato M. , Modena M. , Santini S. , Schiavon R.
orthopedicsarticle2011barbera-p bonato-m modena-m santini-s schiavon-r
One-step cartilage repair in the kneeCollagen-covered microfracture and autologous bone marrow concentrate. A pilot study.

Authors: Busilacchi A. , Calcagno S. , Cecconi S. , Enea D. , Manzotti S.
orthopedicsarticle2015busilacchi-a calcagno-s cecconi-s enea-d manzotti-s
Odontogenic myxoma: a case of conservative surgical approach for an adolescent patient.In this case report, an odontogenic myxoma located in the mandible in a 13-year-old female patient treated by a conservative surgical approach following enucleation and curettage was presented.

Authors: Çakır M. , Samur Ergüven S. , Sancar Ataç M. , Yıldırım B.
dentistryarticle2015cakir-m samur-erguven-s sancar-atac-m yildirim-b
Osteoplant acts on stem cells derived from peripheral blood.The osteoplant is an equine, flexible, heterologous, deantigenic, cortical, and spongy bone tissue, totally reabsorbable, used for implantation of bone tissue, to restore skeletal, even weight-bearing structures. However, how the osteoplant alters osteoblast activity to promote bone formation is poorly understood.

Authors: Brunelli G. , Carinci F. , Girardi A. , Palmieri A. , Sollazzo V. , Spinelli G. , Zollino I.
2010Experimental data
experimental-dataarticle2010brunelli-g carinci-f girardi-a palmieri-a sollazzo-v spinelli-g zollino-i
An enzymatic deantigenation process allows achieving physiological remodeling and even osteopromoting bone grafting materials

Authors: Ludovichetti M. , Maggi S. , Pagnutti S.
2007Enzymatic process
enzymatic-processarticle2007ludovichetti-m maggi-s pagnutti-s