{"id":14595,"date":"2026-09-19T09:51:31","date_gmt":"2026-09-19T08:51:31","guid":{"rendered":"https:\/\/www.bioteckacademy.com\/?p=14595"},"modified":"2026-09-19T09:52:49","modified_gmt":"2026-09-19T08:52:49","slug":"biomateriales-heterologos-colageno-beta-tcp-estudio-in-vitro","status":"publish","type":"post","link":"https:\/\/www.bioteckacademy.com\/es\/biomateriales-heterologos-colageno-beta-tcp-estudio-in-vitro\/","title":{"rendered":"Cuando el col\u00e1geno marca la diferencia: estudio comparativo In Vitro entre biomateriales heter\u00f3logos con diferentes formas de col\u00e1geno y \u03b2-TCP"},"content":{"rendered":"\r\n<p class=\"wp-block-paragraph\">Nos complace anunciar la publicaci\u00f3n de una nueva ficha de Bioteck Academy que resume un estudio <em>in vitro<\/em> publicado recientemente en la revista internacional <em>Minerva Dental and Oral Science. <\/em><\/p>\r\n\r\n\r\n<p class=\"wp-block-paragraph\"><em><br \/>\r\n<\/em>La investigaci\u00f3n, llevada a cabo en los laboratorios del Hospital San Raffaele de Mil\u00e1n y coordinada por el profesor Danilo Alessio Di Stefano, presidente electo de la IAO, ha evaluado el comportamiento biol\u00f3gico de dos sustitutos \u00f3seos de origen equino, compar\u00e1ndolos con un biomaterial sint\u00e9tico a base de fosfato tric\u00e1lcico \u03b2 (\u03b2-TCP).<\/p>\r\n<p>&nbsp;<\/p>\r\n\r\n\r\n<p class=\"wp-block-paragraph\">Los biomateriales equinos analizados consist\u00edan en un injerto con <strong>col\u00e1geno nativo conservado (Osteoplant\u00ae\/Osteoxenon\u00ae)<\/strong> y un injerto con <strong>col\u00e1geno hidrolizado (Bio-Gen\u00ae)<\/strong>, ambos obtenidos mediante el proceso de desantigenizaci\u00f3n enzim\u00e1tica a temperatura controlada <strong>Zymo-Teck\u00ae<\/strong>, patentado por <strong>Bioteck SpA<\/strong>.<\/p>\r\n<p>&nbsp;<\/p>\r\n\r\n\r\n<p class=\"wp-block-paragraph\">Los materiales se sometieron a ensayos <em>in vitro<\/em>, evaluando aspectos clave como la vitalidad celular, la capacidad de adhesi\u00f3n, el potencial de diferenciaci\u00f3n osteog\u00e9nica y la expresi\u00f3n de genes implicados en los procesos de formaci\u00f3n y remodelaci\u00f3n \u00f3sea.<\/p>\r\n<p>&nbsp;<\/p>\r\n\r\n\r\n<p class=\"wp-block-paragraph\">Los resultados pusieron de manifiesto una respuesta biol\u00f3gica limitada en las c\u00e9lulas expuestas al \u03b2-TCP, mientras que las cultivadas sobre los biomateriales equinos mostraron una mayor actividad osteog\u00e9nica, con distintos niveles de diferenciaci\u00f3n celular. En concreto, el biomaterial que contiene col\u00e1geno preservado demostr\u00f3 la mayor capacidad para favorecer los procesos de maduraci\u00f3n osteobl\u00e1stica y estimular los mecanismos biol\u00f3gicos asociados a la regeneraci\u00f3n \u00f3sea.<\/p>\r\n<p>&nbsp;<\/p>\r\n\r\n\r\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.bioteckacademy.com\/wp-content\/uploads\/2026\/07\/RES_SCH6_ES_web.pdf\">\u00a1Lee aqu\u00ed la ficha completa!<\/a><\/p>\r\n\r\n\r\n<p class=\"wp-block-paragraph\">&nbsp;<\/p>\r\n<p><strong>\u00bfQuieres saber m\u00e1s? \u00a1Nos encontrar\u00e1s en el Congreso de la IAO del 8 al 10 de octubre en Padua y en el TRAUMAMEETING de Riccione del 7 al 9 de octubre!<\/strong><\/p>\r\n","protected":false},"excerpt":{"rendered":"<p>Nos complace anunciar la publicaci\u00f3n de una nueva ficha de Bioteck Academy que resume un estudio in vitro publicado recientemente en la revista internacional Minerva Dental and Oral [&hellip;]<\/p>\n","protected":false},"author":7,"featured_media":14597,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[3],"tags":[],"class_list":["post-14595","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sin-categorizar"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Col\u00e1geno y \u03b2-TCP en biomateriales heter\u00f3logos: estudio in vitro<\/title>\n<meta name=\"description\" content=\"Un estudio in vitro compara biomateriales heter\u00f3logos con col\u00e1geno conservado o hidrolizado y \u03b2-TCP, evaluando la respuesta celular.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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