HISTOMORPHOMETRIC ANALYSIS OF BONE REGENERATION AFTER USE OF PROPOLIS VERSUS NANOBONE GRAFT MATERIALS FOR THE MANAGEMENT OF CLASS II FURCATION DEFECTS IN DOGS

The use of a Collagen Membrane to cover a synthetic graft in an animal study

In this study the authors compared the effectiveness of NanoBone graft and propolis material on the inter-radicular bone regeneration in Mongrel dogs.
A split mouth design was carried out using the third and fourth mandibular premolars of 3 healthy mongrel dogs. A total of 12 grade II furcation defects were surgically created. The defects in the right side were treated with NanoBone graft and then a collagen membrane was used to cover the defects. In the left side the defects were treated with propolis and then covered with collagen membrane. The dogs were sacrificed after 4 weeks. Segments of the jaw bone containing the defects were then dissected out and prepared for histological evaluation.
Both percentage of bone fill and percentage of bone surface area in defects treated with propolis powder were higher than those in NanoBone-filled defects.
Both propolis and NanoBone graft materials have bone regenerative effects with higher ability of propolis to regenerate bone.

PRODUCTS USED: Biocollagen Membrane

Alexandria Dental Journal