MODELING AND REMODELING: THE CELLULAR MACHINERY RESPONSIBLE FOR THE GAIN AND LOSS OF BONE’S MATERIAL AND STRUCTURAL STRENGTH

The basis of the remodeling process occurring in bones

This Chapter describes the basis of bone remodeling, the concept of Basic Multicellular Unit (BMU) and the composition of the bone.

It explains how the bone can be resistant and flexyble, light and strong at the same time. 

It provides a very detailed rationale used by Nature to develop bones with different features depending from their location and the function they should provide.