To improve the quality of the repair of alveoli after extractions can be used biomaterial. The objective of this study is to compare the bone healing process between Bio-gen and GenOx. We used six Beagle dogs. There were bilateral extraction of three premolars. On the right in the first well was applied Bio-Gen, was maintained only in the second and third clot Genox. On the left side was applied in the first well Bio-Gen + PRP clot + PRP in the second and third Genox + PRP. After 30, 60 and 90 days the dogs were euthanized, the jaws were dissected and submitted to the process for histological analysis of bone formation using the Image-Pro Plus. Among the groups studied Bio-Gen + PRP showed the best results, with an option for the repair of the alveolus.