This article describes the use of PRF in bilateral direct sinus lift case. Around 20 ml of blood is collected from the patient for each side procedure in the vacutainer tubes and then placed immediately before the coagulation cascade begins in a centrifugal machine at 3000 rpm for 10 min and the middle fraction containing the fibrin clot is then collected to obtain the PRF. Sinus cavities after lifting the membrane was filled with PRF in combination with DFDBA and FDBA. The post-operative radiograph showed faster healing as compared to physiologic healing. However, the preparation being strictly autologus, the amount of PRF obtained is limited.