The present case report concerns a 60-year-old patient affected with generalized stage III grade B periodontitis, who had been treated at the author’s office for 18 years, and who, during periodic four-monthly oral hygiene sessions, identified periodontal pockets 6 mm deep at the level of element 26. Treatment involved the use of a new collagen hydrogel, H42, following nonsurgical laser-assisted periodontal instrumentation performed in a site specific manner. At 1 and 2 months follow-up, significant reduction in infiammation, significant improvement in mucosal seal quality, and probing values (PD) were in the normal range. At 3 months follow-up, the periodontal probe detected a 2 mm probing value (PD), associated with a 2 mm recession, for an overall reduction in probing depth of 4 mm (PD), and also in CAL from 6 to 4 mm. In addition, periapical radiographs at 3 months indicated a slight improvement in bone mineralization of the treated site, quite significant in such a short time.
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