TREATMENT OF SIMPLE BONE CYST WITH BONE MARROW CONCENTRATE AND EQUINE-DERIVED DEMINERALIZED BONE MATRIX INJECTION VERSUS METHYLPREDNISOLONE ACETATE INJECTIONS: A RETROSPECTIVE COMPARATIVE STUDY

The use of an equine enzymatically deantigenated and demineralized bone paste in association with autologous BMC in patients with bone cysts

The aim of this study was to compare the outcome of intra-lesional autologous bone marrow concentrate (BMC) and equine derived demineralized bone matrix (EDDBM) injections with methylprednisolone acetate injections in patients with simple bone cyst. Clinical records and radiographs of 53 consecutive patients (37 females,and 16 males; mean age: 10.6+/-1.53 years) treated between 2006 and 2016 were retrospectively reviewed. At a minimum follow-up of 24 months, success rate (Neer/Cole score 3 and 4) was higher in EDDBM+BMC group (83.3% vs 58.6%; p=0.047).  Treatment with BMC+EDDBM injections may provide better results with a single procedure than 3 methylprednisolone acetate injections and represent an interesting alternative for the treatment of unicameral bone cysts. 

PRODUCTS USED: Osteoplant Activagen Injectable Paste