Odontoiatria e Maxillofacciale

A RETROSPECTIVE PRELIMINARY HISTOMORPHOMETRIC AND CLINICAL INVESTIGATION ON SINUS AUGMENTATION USING ENZYME-DEANTIGENIC, COLLAGEN-PRESERVING EQUINE BONE GRANULES AND PLASMA RICH IN GROWTH FACTORS

2021
Autore : Vinci R., Gherlone E., Di Stefano D.A., Capparè P.

The combination of the enzyme-deantigenated bone substitute and of the autologous derivative Platelet Rich Growth Factor

Enzyme-deantigenic equine bone (EDEB) is a substitute of autogenous bone. Mixing it with plasma rich in growth factors (PRGF) seems a viable option to achieve enhanced bone formation in alveolar bone augmentation surgeries. This retrospective study aims to first report the histomorphometric and clinical outcomes achieved when using the EDEB/PRGF mixture for performing sinus augmentation procedures followed by delayed implant placement. Records of 11 patients who underwent 14 sinus augmentation surgeries using EDEB/PRGF followed by delayed implant placement were retrospectively collected and analyzed to assess histomorphometric data concerning newly formed bone (NFB) and residual biomaterial (RB) recorded at implant placement, marginal bone loss (MBL) values of implants placed in the augmented sinuses, and implant and prosthetic success and survival rates. At 5.6 +/- 1.1 months after grafting, NFB and RB were 34.0 +/- 9.1% and 11.3 +/- 2.2% respectively, and no histologic signs of inflammation or immune reaction were observed in any of the 34 bone biopsies being collected. Further, 86.5 +/- 4.3 months after implant placement, MBL was 0.40 +/- 0.07 mm. No implant or prosthesis failed, and the implant success and survival rates were 100%. Within the limitations of the present study, grafting EDEB/PRGF for lateral sinus augmentation and delayed implant placement seems to be safe. 

PRODUCTS USED: Osteoxenon Granules Mix, Biocollagen Membrane

International Journal of Implant Dentistry
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