CHONDROGRID IN THE TREATMENT OF MUSCLE INJURIES: A CASE SERIES

Use of hydrolyzed collagen in the treatment of muscle injuries: preliminary case report collection with clinical and ultrasound evidence.

Muscle injuries account for more than one-third of sports-related injuries, and their incidence increases with the age of athletes. Soleus-gastrocnemius injuries are the most common in high-speed running, although in other sports (e.g., soccer) the quadriceps and rectus femoris are more involved. Interestingly, at the muscle level, collagen plays a significant role as a scaffold for muscle fibers. In fact, collagen forms a network of intramuscular connective tissue, which is organized on three levels: endomysium (connective tissue that surrounds the single muscle fiber), perimysium (connective tissue that surrounds fascicles of muscle fibers) and epimysium (connective tissue that surrounds the entire muscle). Recently, a new infiltrative device based on hydrolyzed collagen (CHondroGrid, Bioteck Spa, Arcugnano – Vicenza, Italy) has been successfully introduced for the treatment of pain symptoms and functional recovery in knee osteoarthritis and the treatment of rotator cuff tendinopathy. Hydrolyzed collagen consists of collagen peptides that, when injected, rapidly diffuse within the site, going directly to strengthen the damaged structures and promoting reduction of pain symptomatology and functional recovery. These preliminary results demonstrate that treatment with low molecular weight hydrolyzed collagen (CHondroGrid) can be effective in the treatment of grade 1 and 2 muscle injuries. The observed improvement seems to be evident from the time the patient underwent collagen injection. The observed improvement seems to be evident from the first administration and in continuous progression up to 3 months of follow-up.

Product used: Chondrogrid, CHG-004