The case concerns a female patient who presented with bleeding and pain when performing oral hygiene at the peri-implant mucous membranes. The intraoral examination showed inflammation of the mucous membranes around the abutments of the two implants, while the CBCT scan showed conspicuous bone resorption with two peri-implant resorption cones that extended to approximately one- third of one implant and approximately half of the other. The treatment plan suggested to the patient entailed cleaning of the peri-implant surface, followed by bone regeneration with a bone substitute (Calcitos) and a membrane (Biocollagen). Three months after the procedure, the X-ray showed the implant bodies were still completely inserted in the regenerated crestal bone. The patient did not report any spontaneous or evoked symptoms and no soft tissue damage was observed.