The need to increase the predictability of successful periodontal regeneration has led to the use of endogenous regenerative therapy in combination with osteoconductive scaffolds based on the principles of tissue engineering. The introduction of Choukroun’s Platelet Rich Fibrin (PRF), has revolutionalized the field of dentistry. PRF, a rich source of autologous growth factors and cytokines, is an upcoming therapeutic approach in the management of periodontal osseous defects. The present case report describes the treatment of an intrabony defect with platelet rich fibrin along with xenograft.
In the present report, a considerable reduction in PPD and CAL gain (5mm each) was observed 9 months post-operatively. Bone fill up to 60-70% was evident at 9 months with associated crestal bone formation, suggesting the arrest of disease activity.