OSTEO-PROMOTING ACTIVITY OF OSTEOPLANT ANGIOSTAD IN VITRO

There is an increasing need for an appropriate and readily-available material to reconstruct large bone defects, one of the most significant problems in the dental and maxillo-facial fields. The in vitro study examines the effects of OSTEOPLANT ANGIOSTAD, a product developed to increase osteoinductivity.

RESULTS: OSTEOPLANT ANGIOSTAD preserved MSC’s viability and improved their capacity to release TGF-b1. It also increased in vitro wound healing by MSC and migration of endothelial cells.

CONCLUSION: The results show that, since it increases the production by MSC of proangiogenic factors such as TGF-beta and promotes endothelial cell migration, OSTEOPLANT ANGIOSTAD may be an appropriate adjunct to accelerate the osteointegration of bone substitutes.

PRODUCTS USED: OSTEOPLANT ANGIOSTAD