The sheet summarizes part of the results of an article published in Biomaterial Science in 2016. This study involved the analysis of the biological behavior of the Activabone Moldable Paste bone substitute (Bioteck). The paste is composed of corpuscular constituents of equine origin. A first analysis assessed the effect of Activabone on cell vitality. For this test, the researchers used human bone marrow stromal cells. A second experiment consisted in checking if the same cells, in the presence of Activabone, modified their gene expression profile. These results show that Activabone, when grafted in vivo, may significantly promote the formation of new bone tissue.