The present case involves a 53-year-old patient, a smoker, who presented to observation for her usual periodic checkup complaining of bleeding and gingival pain during oral hygiene maneuvers at the level of two implants located at position 4.6 and 4.7. Following the performance of a CBCT for other reasons, marked peri-implant bone resorption could be seen. Following the diagnosis of peri-implantitis affecting both implants, the patient was offered a plan of treatment that included cleaning and decontamination of the peri-implant area followed by GBR surgery, performed by using a slow-resorbing bone substitute of equine origin. This latter was obtained by thermal elimination of antigens, ensuring a prolonged temporal stability of the bone profiles during regeneration, and a collagen membrane, also of equine origin to protect the graft.
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